ANGIOFIBROMA NASOFARINGEO PDF

Introduction: Juvenile nasopharyngeal angiofibroma is a rare, highly .. Luiz A CR, Romualdo S LT, Fava A S. Angiofibroma nasofaríngeo: revisão de literatura. Juvenile nasopharyngeal angiofibroma (JNA) is a rare benign tumor arising predominantly in the nasopharynx of adolescent males. It is an aggressive. Juvenile nasopharyngeal angiofibromas (JNA) are a rare benign but locally aggressive vascular tumor. Epidemiology Juvenile nasopharyngeal angiofibromas.

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Juvenile nasopharyngeal angiofibroma

Intracranial juvenile nasopharyngeal angiofibroma. Retrospective, descriptive study conducted after approval from the Ethics Committee of the Federal University of Sergipe protocol Case 2 Case 2. The nature of juvenile nasopharyngeal angiofibroma.

We started the first surgical dissection of the tumor through a unciform process incision, anterior and posterior ethmoidectomy with wide exposure of the lamina papyracea and the ethmoid roof. These tests have led to the formulations of multiple classification methods, including the FischRadkowskiAndrewsBremerand Antonelli methods 1,4,5,7,8.

Arch Otolaryngol Head Neck Surg. Follow-up after surgery to detect recurrence. Ann Otol, Rhinol Laryngol. They may extend towards the nasopharynx, which includes the maxillary, ethmoid, and sphenoid sinuses.

Juvenile nasopharyngeal angiofibroma and familial adenomatous polyposis: Connective tissue was fibro-cellular with irregular pattern and plump fibroblasts [ Figure 6 ].

Angiofibroma nasofaríngeo juvenil – Wikipedia, la enciclopedia libre

The IGFII gene undergoes maternal imprinting, that is, expresses normally only the paternal allele J Clin Imaging Sci. Tumor size was not associated with bleeding.

The 3 patients who underwent combined surgeries experienced intraoperative bleeding, requiring nasal packing and replacement of blood products during surgery.

The terms chosen for the research were: Reviewing JNA’s pathogenesis, emphasizing genetic and molecular aspects. Hippocrates first described this tumor in the 5 th century B.

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To theory about the JNA pathogenesis could have explained if the initial event of its development occurs in the endothelium or in the tumor stroma.

However, as in any invasive procedure, embolization presents risks that should be fully explained to the patients Angiofibroa of JNA is made by complete history, clinical examination, radiography, nasal endoscopy and by using specialized imaging techniques such as arteriography, computer tomography and magnetic resonance imaging. The presentation is typically with obstructive symptoms, epistaxisand chronic otomastoiditis due to obstruction of the Eustachian tube.

Endoscopic Surgery of Nasopharyngeal Angiofibroma

A retrospective case study of five cases of NAJ underwent surgery solely with endoscopic technique of two surgeons. DSA digital subtraction angiography of carotid artery to see the extension of tumors and feeding vessels. Treatment trends in patients during 40 years. Endoscopic Surgery for Angiofbiroma Angiofibroma: Hormonal receptors in juvenile nasopharyngeal angiofibroma.

A typical staghorn type appearance is seen.

Page views in Technique The five patients in this series had treatment by endoscopic nasoangiofibroma being that for such surgery was performed with access through both nostrils, the technique of two surgeons and four hands technique.

JNA being an aggressive tumor may recur naosfaringeo.

Nasopharyngeal angiofibroma: Our experience and literature review

Endoscopic Laser-assisted excision of juvenile nasopharyngeal angiofibromas. Invasion of the intracranial region may lead to cranial nerve palsy.

Many angiofibrona highlight the benefit of preoperative arterial embolization to control bleeding intraoperative 16,29, Examinations such as computed tomography, nuclear magnetic resonance and even nasal endoscopy can clearly establish the extent of the tumor, its pattern of spread, and consequently, surgical planning 10 11 12 16 17 18 Extended osteoplastic maxillotomy for total excision of giant multicompartmental juvenile nasopharyngeal angiofibroma.

This syndrome is a dominant autossomal condition characterized by several adenomas in the gastrointestinal tract, trend for the development of adenocarcinomas and extraintestinal manifestations. Endoscopic surgery alone or with other conventional techniques was safe for the treatment of angiofibromas of different stages.

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The sex selectivity seen in JNA angiofibrmoa be explained by intranuclear accumulation of androgen receptor and beta-catenin, a co-activator which increases the tumor sensitivity to androgynous.

In another large series, twenty four cases out or twenty seven had a VEGF significant marking, while the TGF-beta marking was found in fourteen cases and angiofkbroma could exercise a role in the tumor pathogenesis by the promotion of angiogenesis and cellular angiogenesis Tumor volume was not associated with bleeding in patients with and without clamping.

Extensive bony destruction is usually not a feature, but rather bone is remodelled or resorbed. None of our patients experienced complications due to embolization. Therefore, there are nazofaringeo challenges in the JNA immunopathogenesis understanding, such as the phenotypic study of in situ antitumoral immune response.

How to cite this article. No encapsulation was noted [ Figure 4 ]. We analyzed findings in 20 patients who underwent surgery between and In the JNA, anti-androgenic agents like flutamide nassofaringeo reduce the growth rate of the JNA in vitro 40and besides the androgen receptor, other steroid receptors have already been detected 39, It shows very aggressive behavior due to local invasiveness and is associated with various symptoms.

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