ESTUDIO WHI, REVISTA DE MENOPAUSIA, SALUD, REVISTAS MÉDICAS. Actualidad Inmediata Debido a la importancia de esta investigación y al impacto en. WHI. Progestin. Estrogen. Tibolone. Cardiovascular disease. Tromboembolic disease . Boletín de la Asociación Española para el Estudio de la Menopausia, . Los trastornos de la menopausia pueden ser evitados y combatidos Sin embargo, recientes estudios, como el estudio WHI, han puesto en duda los beneficios.

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Br J Nutr, 89pp. Phytoestrogens and carcinogenesis—Differential effects of genistein in experimental models of normal and malignant rat endometrium. Serum enterolactone concentration is not associated with breast cancer risk in a nested casecontrol study. Urinary excretion of phytoestrogens and risk of breast cancer among Chinese women in Shangai. Dietary intake of phytoestrogens is associated with a favorable metabolic cardiovascular risk profile in postmenopausal US women: There is a higher event rate among users of digitalis in the hormone group compared with the placebo groups [ 6 ].

Menopausal estrogen and estrogen-progestin replacement therapy and breast cancer risk.

The effect sstudio a soy rich diet on the vaginal epithelium in postmenopause: National Institutes of Health, What is important is the best possible approach to preventive medicine in a mid-aged woman. Trends in the incidence of coronary heart disease and changes in diet and lifestyle in women. Intern J Cancer, 81pp. Folia Clin Intern, 49pp. Menopause, 6pp. High dietary phytoestrogen intake is associated with higher bone mineral density in postmenopausal but non premenopausal women.

Failure of estrogen plus progestin therapy for prevention. Changes in symptoms, lipid and hormone levels after the administration of a cream with phytoestrogens in the climateric: Soy intake and the maintenance of peak bone mass in Hong Kong Chinese women. In the protocol of the study it is mentioned that women had to have a base line mammography [ 5 ].


Van der Schow, P. Thus this fixed excessive dose for older women does not necessarily reflect optimal good clinical practice and is not estudlo by any responsible gynaecologist.

Risk and benefits of estrogen plus progestin in healty postmenopausal women. Principal results from the Women’s Health Initiative controlled randomized trial. Phytoestrogens do not influence lipoprotein levels or endothelial function in healthy postmenopausal women. J Bone Miner Res, 16pp.

Isoflavonas y menopausia | Clínica e Investigación en Ginecología y Obstetricia

Breast and uterine effects of soy isoflavones and conjugated estrogens in postmenopausal female monkeys. First came the results from the estrogen plus progestin arm [2,3], which were summarized by menopausiw investigators as follows: WHIMS-Y provided an unprecedented chance to examine the hypothesis that HT may have protective effects on cognition in younger postmenopausal women aged 50—54 years.

However, interim reports on women on estrogens alone did not show adverse CV or breast cancer crossing the predetermined safety boundaries, and this part of the trial thus continues.

Climateric, 3pp. Menopause, 8pp. Obstet Gynecol,pp. It must be made clear that the concept of HRT does not mean that all postmenopausal women must be always under hormonal treatments [ 11 and 12 ]. Clin Invest Gin Obst, 30pp.

Evaluation of soy phytoestrogens for the treatment of hot flashes in breast cancer survivors: Controlled Clin Trials ; The estrogen-alone data were published in and were estuduo once again in two separate papers [4,5]: Am J Clin Nutr, 72pp. Estrogen plus progestin and the risk of coronary heart disease. Efficacy of a soy rich diet in preventing postmenopausal osteoporosis.


Effects of genistein and hormone-replacement therapy on bone loss in early postmenopausal women: Influence of estrogen plus progestin on breast cancer and mammography in healty postmenopausal women. JAMA,pp. Those data describe increased risk of an entire population, not the increased risk for individual women [ 3 ]. It must be emphasized that the WHI report stresses that the results do not necessarily apply to lower dosages of those drugs, to other formulations of oral estrogen and progestin or to estrogens and progestins administered through the transdermal route [ 1 ].

Differences in effects between cognitive domains suggest that more than one mechanism may be involved. The best RCT still trumps the best observational study. J Clin Endocrinol Metab, 87pp. At present, in some European estudiio the indication for prevention of postmenopausal osteoporosis by HRT will be re-assessed according to public statements of drug licensing authorities.

In a re-analysis of HERS follow-up during 6. The Management of the Menopause. You can change the settings or obtain more information by clicking here.

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Fertil Steril, 77pp. Breast cancer risk following long-term oestrogen and oestrogen-progestin replacement therapy. This concept failed in this specific, large group of women studied. The increased risk of breast cancer became apparent only after the fourth year of treatment. Obst Gynecol, 87pp.

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