Diagnostic de l’intoxication digitalique et son traitement. Ferrero C. Author affiliations. Clinique universitaire de Médecine Interne, Hôpital Cantonal, Genève . Request PDF on ResearchGate | Intoxication digitalique en période néonatale: rôle de la déshydratation | Background Despite the great progress which has. Request PDF on ResearchGate | Intoxication digitalique massive. Traitement par hémoperfusion sur résine Amberlite XAD 4 | Haemoperfusion over amberlite.

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Digoxin immune Fab therapy in the management of digitalis intoxication: Assessment of the synergistic relationship between serum calcium and digitalis. At digiyalique concentrations, they increase the ventricular excitability. Copyright and License information Disclaimer. As per the Law relating to information storage and personal integrity, you have the right to oppose art 26 of that lawaccess art 34 of that law and rectify art 36 of that law your personal data.

Kinetics of the Fab fragments of digoxin antibodies and of bound digoxin in patients with severe digoxin intoxication. These electrical changes happen to the T wave and the ST segment with a flattening of the T wave, which becomes negative but remains asymmetric, lowering of the J-point and a sub-offset of the ST segment characterized by a cupule to the upper concavity called “cupule digitalis” Figure 3.

Médecine thérapeutique

The case reminds us, difitalique with the data in the literature, the criteria of wrong prognoses in massive digitalis intoxication in the child and the indications for anti-digoxin antibodies. Support Center Support Center. The high cost often limits the access to the hospital centers [7].


Am J Emerg Med 9: Table 1 Pharmacokinetic characteristics. Associated Data Supplementary Materials. Review of the literature.

Phenytoin diphenylhydantoin treatment of massive digoxin overdose. This text will be overwritten by jQuery. The first may make appeal to a diagnosis in the case of a patient treated by digitalis. You may thus request that your data, should it be inaccurate, incomplete, unclear, outdated, not be used or stored, be corrected, clarified, updated or deleted. National Center for Biotechnology InformationU.

Outline Masquer le plan. A second Antidote dose is founded digitaliuqe the onset of clinical signs associated with a pejorative factor Table 4. Nouv Presse Med Access to the PDF text. Headache, myalgia, asthenia are also frequent.

Journal page Archives Contents list. Automatism disturbances To the ventricular floor it may consist of a ventricular extra systoles, more or less frequent, and tachycardia or ventricular fibrillation. It is recalled that the signs of glycosides digitalis impregnations may manifest at therapeutical doses.

John Libbey Eurotext – Médecine thérapeutique – Intoxication aiguë par la digoxine

Journal List Br Heart J v. Drug Interactions of Digitalis. Review of the literature G. Access to the full text of this article requires a subscription.

Massive digoxin ingestion. Report of a case and review of currently available therapies.

Risk factors and manifestations of digoxin toxicity in the elderly. The treatment consists of electrolytic controls, supplements when needed intoxiation anti-arrhythmic agents if there is a significant presence of dysrhythmias. However, the insertion of the probe in the Ventricle risks inducing a ventricular arrhythmia and therefore it is suggested to administrate lidocaine first [5].

The digibind study advisory panel.


Allergic histories and reactions of patients treated with digoxin immune Fab ovine antibody. Therefore, more calcium is stocked in the sarcoplasmic reticulum, where more calcium is available to the next cellular depolarization and increase in the myocardial contraction Figure 2. Equimolar Neutralization Semi-molar neutralization In the presence of a single pejorative factor: Arhythmia; Digoxin; Digitalis; Intoxication; Immunotherapy Introduction The digitalis glycosides are known for long to the medical world.

Finally, the anti digitalic antibodies can reverse the effect of digoxin in neutralizing its free fraction in serum and extracellular [5]. J Toxicol Clin Toxicol Intensive Care Med Am J Med Sci. Recent studies set this margin to 0. The clinical presentation of acute intoxication differs a little from that of a chronic intoxication. Correlation of serum magnesium levels and cardiac digitalis intoxication.

The digoxin has a large volume of distribution 5.

Voltage-time course and the effect of acetylcholine on atrial and nodal cells of the rabbit heart. J Pharmacol Exp Ther. Recognition and management of digitalis toxicity.

If you want to subscribe to this journal, see our rates You can purchase this item in Pay Per View: It is part of the arsenal therapeutic of atrial fibrillation, supraventricular tachycardia and congestive heart failure.

Which decreases the sodic transmembrane gradient responsible for moving out calcium by the antiporter, digitaljque calcium continues to enter to the cell in each depolarization.

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